Development of Nanocomposite Coatings.

This Special Issue in Nanomaterials, "Development of Nanocomposite Coatings", was set up with the aim to provide authors with an opportunity to showcase their latest developments in this field [...].

A Multiscale Overview of Modelling Rolling Cyclic Fatigue in Bearing Elements.

During service, bearing components experience rolling cyclic fatigue (RCF), resulting in subsurface plasticity and decay of the parent microstructure. The accumulation of micro strains spans billions of rolling cycles, resulting in the continuous evolution of the bearing steel microstructure. The bearing steel composition, non-metallic inclusions, continuously evolving residual stresses, and substantial work hardening, followed by subsurface softening, create further complications in modelling bearing steel at different length scales. The current study presents a multiscale overview of modelling RCF in terms of plastic deformation and the corresponding microstructural alterations. This article investigates previous models to predict microstructural alterations and material hardening approaches widely adopted to mimic the cyclic hardening response of the evolved bearing steel microstructure. This review presents state-of-the-art, relevant reviews in terms of this subject and provides a robust academic critique to enhance the understanding of the elastoplastic response of bearing steel under non-proportional loadings, damage evolution, and the formation mechanics of microstructural alterations, leading to the increased fatigue life of bearing components. It is suggested that a multidisciplinary approach at various length scales is required to fully understand the micromechanical and metallurgical response of bearing steels widely used in industry. This review will make significant contributions to novel design methodologies and improved product design specifications to deliver the durability and reliability of bearing elements.

Enhanced Mechanical Properties and Microstructure of Accumulative Roll-Bonded Co/Pb Nanocomposite.

Lead composites have been used as anodes in the electrowinning process to produce metals such as copper and zinc. Manufacturing stable lead anodes with appropriate mechanical and chemical properties is required to improve the performance of the electrowinning process. In this study, an accumulative roll bonding (ARB) method was used to fabricate a Co/Pb nanocomposite. Utilizing the ARB method can help us to achieve a uniform structure with enhanced mechanical properties via severe plastic deformation. The results showed that suitable tensile properties were obtained in Pb-0.5%Co-10pass samples. The tensile strength and strain of these samples were 2.51 times higher and 83.7% lower than that of as-cast pure Pb. They also showed creep resistance and hardness up to 1.8 and 2.5 times more than that of as-cast pure Pb. The ARB technique uniformly distributed Co particles in the Pb matrix. The enhanced strength of Pb samples was observed in the composite including grain sizes of less than 50 nm as a result of hindering the recovery phenomenon. The particle size of the Co distributed in the Pb matrix was 353 ± 259 nm. Compared to conventional methods, the ARB process improved the mechanical properties of Co/Pb composites and can open a new horizon to fabricating this composite in metal industries.

Iodoxolone-based hypervalent iodine reagents.

The fast access to simple (Z)-3-iodo acrylic acid derivatives which can be easily oxidized to the corresponding hypervalent iodine(III) reagents is described. They can be used for various reactions with superior or similar reactivity as conventional hypervalent iodine(III) reagents.

Clearance of circulating tumor cells after excision of primary colorectal cancer.

OBJECTIVE: To establish whether the prevalence of positive reverse transcriptase-polymerase chain reaction (RT-PCR) results decreased during the first 3 months after colorectal cancer excision, and to assess whether persistence of RT-PCR positivity after primary colorectal cancer excision was related to tumor stage or locally advanced and metastatic disease. METHODS: Systemic venous blood was collected from patients with colorectal cancer before and at intervals up to 12 weeks after surgery. RNA was extracted from the mononuclear cell fraction of the blood samples and subjected to RT-PCR using specific primers for carcinoembryonic antigen mRNA and cytokeratin-20 mRNA. Healthy individuals with no history of cancer were used as controls. RESULTS: The results of RT-PCR were positive in 81 of 116 patients with colorectal cancer before surgery, with no significant differences in preoperative prevalence by Dukes stage or presence of locally advanced or metastatic disease. There was a significant decrease in the prevalence of RT-PCR positivity at 24 hours after surgery compared with before surgery. On subgroup analysis by Dukes stage, only the decrease in Dukes A and B patients reached significance. Seven of the 143 controls were RT-PCR positive. CONCLUSIONS: Circulating tumor cells were present before treatment in most patients with colorectal cancer regardless of tumor stage or metastases. Clearance of circulating tumor cells within 24 hours of colorectal cancer excision was greatest in tumors with the best prognosis.